Hiring: Vice President / Senior Vice President, Clinical Development Lead – Immunology & Program Leadership Company: Flagship Pioneering Location: Cambridge, MA Job Posted Time: 2026-09-02 17:58:09 Employment Type: Full-time Target Skills & Keywords: Clinical Development, Immunology, Program Leadership, Translational Medicine, Phase I & II Studies, IND, Human Proof of Concept, Cross-Functional Integration, Regulatory Affairs, Clinical Operations, Biometrics, Safety, CMC, Commercial, Business Development, Portfolio Strategy, Governance, Dose Selection, Endpoint Strategy, Indication Prioritization, Physician-Scientist Experience: - Highly accomplished clinical development leader with deep expertise in Immunology - Demonstrated Program Leadership experience - Seasoned physician-scientist with deep translational medicine expertise - Proven track record of advancing complex immunology programs - Experience leading cross-functional teams and influencing organizational strategy - Experience operating effectively in a dynamic biotechnology environment - Experience advancing programs from early translational stages through IND and early clinical development - Experience leading Phase I and II studies Required Skills: - Ability to lead overall clinical development strategy for multiple immunology programs across early development - Expertise in designing and overseeing integrated clinical development plans aligned with scientific rationale, patient needs, competitive positioning, and corporate objectives - Clinical leadership for Phase I and II studies, including protocol design, dose selection, endpoint strategy, and data interpretation - Ensuring clinical programs are executed with scientific rigor, operational excellence, and regulatory compliance - Driving indication prioritization and expansion opportunities - Serving as cross-functional Program Team Leader or senior program representative - Aligning functions around key development objectives, timelines, budgets, risks, and decision points - Leading governance discussions, portfolio reviews, and strategic program planning activities - Partnering closely with Research, Translational Sciences and Medicine, Regulatory Affairs, Clinical Operations, Biometrics, Safety, CMC, Commercial, and Business Development teams - Driving integrated program execution by proactively identifying risks, resolving cross-functional challenges, and enabling rapid, data-driven decision-making - Ensuring alignment between clinical strategy and broader portfolio/business objectives Qualifications: - Physician-scientist with deep translational medicine expertise - Enterprise leader with a strong track record of advancing complex immunology programs - Proven ability to lead cross-functional teams and influence organizational strategy - Ability to operate effectively in a dynamic biotechnology environment - Deep expertise in Immunology - Demonstrated Program Leadership experience Compensation: Not specified Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don’t miss this opportunity to join a forward-thinking team!