Hiring: Vice President, Protease Cleavable Linkers Company: Ridge Bio Location: San Carlos, CA Job Posted Time: 2026-09-12 13:00:15 Employment Type: Full-time Target Skills & Keywords : Machine Learning About the job Qualifications: •Completed a Ph.D. in chemistry, biochemistry, chemical biology, protein engineering, or a related discipline, with deep expertise in protease substrate design and tumor-microenvironment biology with many years of industry experience. •Direct, hands-on industry experience designing protease-cleavable substrates or linkers that advanced into a development candidate. •A demonstrated track record of invention including patents, first-author publications, or named contributions to a molecule that reached clinical development. •Demonstrated capacity to work full-time hours at our Bay Area location and occasional flexibility to travel and complete time-sensitive projects. •Own the protease-cleavable linker design function at Ridge, from protease biology and substrate design through assay strategy and preclinical model design. •Directly manage and mentor scientific teams. •Design in vivo and in vitro models to validate conditionally activated molecules and demonstrate proof of concept to partners. •Partner closely with our ADC and bioconjugation teams to connect linker, conjugation, and protease biology insights. •Present externally to partners and investors. Compensation: •Flexible work environment (work from home / hybrid options) Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!