Hiring: Staff Systems Engineer (Plaque) Company: Heartflow Location: San Francisco, CA Job Posted Time: 2026-09-15 13:00:32 Target Skills & Keywords : Systems Design, Systems Engineering About the job Experience: •B.S. or M.S. in Systems Engineering, Electrical Engineering, Biomedical Engineering, Physics, or a related discipline; Ph.D. preferred. •Occasional domestic and international travel required. •Operational familiarity with plaque ground-truth and reference-standard methods (e.g., IVUS, OCT, histology). •Expertise in imaging performance and accuracy validation, including relevant statistical methods. •Expertise in DICOM and medical imaging interoperability standards (e.g., IHE, HL7/FHIR, PACS integration). Required Skills: •Lead Systems Engineering for Heartflow's plaque analysis products, including concept definition, system architecture, interface definition, product integration, and verification and validation. •Translate coronary plaque biology, progression, and clinical utility, together with product goals, into testable, unambiguous requirements in partnership with cross-functional stakeholders. •Identify, analyze, and manage system-level technical risks using a data-driven approach, collaborating cross-functionally to design and implement mitigations in the product. •Partner cross-functionally with cross-functional teams (Clinical, Research, Product, and Engineering) to drive the requirements and characterization activities that extend and improve plaque analysis. •Define and own the plaque ground truth, in conjunction with the Clinical team, to ensure plaque products are properly validated. •Curate plaque datasets to improve accuracy and validation. •Serve as the primary investigator for plaque-related complaints and escalations, diagnosing root cause and translating findings into a roadmap to resolve them. •Represent Systems Engineering in design reviews, program planning, and cross-functional decision-making, and serve as the plaque subject matter expert in regulatory submissions and audits. Compensation: •$190,000 - $250,000 / year •A reasonable estimate of the base salary compensation range is $190,000 to $250,000, bonus, and equity •A reasonable estimate of the base salary compensation range is $190,000 to $250,000, bonus, and equity. Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!