Hiring: Senior Scientist, Immunology Company: Flagship Pioneering Location: Cambridge, MA Job Posted Time: 2026-09-09 17:58:09 Employment Type: Full-time Target Skills & Keywords: Immunology, T Cell Biology, In Vivo CAR-T Therapy, Flow Cytometry, Humanized Mouse Models, NHP Ex Vivo Analysis, Primary T Cells, Human PBMC, Non-Viral Delivery, Nucleic Acid Modalities, Cytotoxicity Assays, Pre-clinical Disease Models, CRO Collaboration Experience: - PhD in Immunology or a related field with 5+ years of relevant experience - Industry experience preferred - Title will be commensurate with experience - Hands-on experience with in vitro and ex vivo experimental approaches - Experience with pre-clinical disease models Required Skills: - Deep expertise in flow cytometry, including panel design, instrument setup, and data analysis - Experience handling primary T cells, human PBMC, and associated assays to determine T cell function and phenotype - Experience with mouse models and ex vivo tissue processing and analyses - Ability to independently design and execute complex in vitro assays to evaluate CAR-T cell function, including multi-color flow cytometry, cytotoxicity assays, and other functional readouts - Ability to independently design and execute in vivo studies, including humanized mice and NHPs, and conduct ex vivo analysis of immune cells - Experience interacting with CROs or academic collaborators for in vivo study-related activities - Strong experimental protocol development, optimization, and troubleshooting skills - Accurate and timely electronic laboratory notebook record-keeping - Data analysis, interpretation, and communication at lab and project team meetings Qualifications: - PhD in Immunology or related field with 5+ years of relevant experience; industry experience preferred - Deep expertise in flow cytometry, including panel design, instrument setup, and data analysis - Experience handling primary T cells, human PBMC, and associated assays to determine T cell function and phenotype - Experience with mouse models and ex vivo tissue processing and analyses - Experience in humanized mouse models and NHP ex vivo analyses preferred - Experience with in vivo CAR-T strongly preferred - Experience with non-viral delivery technologies and nucleic acid modalities preferred - Highly motivated to execute at the bench with exceptional organizational, problem-solving, communication, and collaboration skills - Entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic, cross-functional team environment - Ability to work both as an independent contributor and as part of a collaborative, multidisciplinary team of scientists Compensation: Not specified Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don’t miss this opportunity to join a forward-thinking team!