Senior Research Associate, LNP Production

Flagship Pioneering - Somerville, MA

Hiring: Senior Research Associate, LNP Production Company: Flagship Pioneering Location: Somerville, MA Job Posted Time: 2026-09-02 17:58:09 Employment Type: Full-time Target Skills & Keywords: LNP formulation, lipid nanoparticles, nucleic acid delivery, mRNA, siRNA, genetic medicines, process development, tangential flow filtration (TFF), mixers, pumping systems, scale-up, characterization, preclinical research, electronic laboratory notebooks Experience: - BS + 5 years of relevant industry or research experience - MS + 3 years of relevant industry or research experience - Hands-on experience with lipid nanoparticle formulation and production, particularly for nucleic acid cargos such as mRNA, siRNA, or other genetic medicines - Experience with a range of LNP processing techniques and equipment across multiple scales, including mixers and pumping systems Required Skills: - Design, formulate, produce, and characterize lipid nanoparticles (LNPs) for nucleic acid therapeutics - Execute LNP production across process scales, from small-scale formulation and optimization through larger-scale production - Operate and develop processes using LNP manufacturing and process-development equipment, including mixers, pumping systems, and tangential flow filtration (TFF) - Troubleshoot formulation and process challenges and drive continuous improvement of LNP production processes - Develop and implement robust, reproducible LNP production and characterization workflows - Maintain accurate documentation in electronic laboratory notebooks - Analyze and communicate experimental results to cross-functional teams Qualifications: - BS or MS in chemical engineering, biochemical engineering, pharmaceutical sciences, chemistry, biology, or a related scientific discipline - Strong technical expertise in LNP formulation and production - Sound scientific judgment and attention to detail - Ability to work effectively in a highly collaborative, fast-paced environment - Highly motivated, collaborative, and relentless problem solver with a passion for genetic medicines Compensation: Not specified Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don’t miss this opportunity to join a forward-thinking team!