Hiring: Senior Principal Scientist - Translational Muscle Biology Company: UCB Location: Cambridge, MA Job Posted Time: 2026-09-13 13:12:44 Employment Type: Hybrid Target Skills & Keywords : Project Management About the job Experience: •PhD with 15+ years or MS Degree with 20+ years in drug discovery, biology, cellular biology, bioengineering or related field. •15+ years or MS Degree with 20+ years in drug discovery, biology, cellular biology, bioengineering or related field. Required Skills: •Team leadership: Supervise and mentor junior scientists, fostering a collaborative and innovative research environment. •Project management: Oversee multiple projects, ensuring timely delivery of milestones and effective resource allocation. •Innovation: Identify and implement new technologies and methodologies to advance muscle cell biology and translational research. •Model Development: Design, characterize and validate primary cell or stem cell/3D models for therapeutic programs. •Assay Execution: Lead the design of cell-based assays to assess therapeutic candidates or validate new gene-editing targets. •Lab bench work: Maintain a minimum 30% hands-on laboratory contribution to support assay execution, model development, and experimental troubleshooting across neuromuscular translational biology programs. •Muscle biology: Drive the design and execution of in vivo and in vitro assays to enhance understanding of neuromuscular disease biology. •Team Collaboration: Collaborate with cross-functional teams to integrate translational biology insights into therapeutic programs or new target proposals. Qualifications: •Proven ability to lead projects, supervise and mentor scientists •Deep knowledge in muscle biology and translational assays. •Strong assay development and drug discovery knowledge. •Strong track record of publishing in high-impact journals and presenting at scientific conferences. •Deep experience with mammalian cell culture, molecular and biochemical assays. •Strong attention to detail, and enthusiasm for learning. •Knowledge in mitochondrial biology is a plus •Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! •UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe, inspired by patients and driven by science. Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!