Hiring: Senior Principal/ Principal Scientist, Computational Safety Company: Boehringer Ingelheim Location: Ridgefield, CT Job Posted Time: 2026-09-10 13:03:53 Target Skills & Keywords : Accessibility About the job Experience: •6+ years of post-doctoral and/or industry experience in drug discovery and development and ≥1 years of experience in safety risk assessment is a must •7+ years of post-doctoral and/or industry experience in drug discovery and development and ≥3 years of experience in safety risk assessment is a must •18 years of age or older Required Skills: •Lead and/or generate in silico target safety assessment strategy development •Develop and deliver integrated computational safety packages to support program and portfolio decisions •Advance AI/ML and multi omics–based models, including foundation models, for safety and liability prediction •Drive AI enabled Adverse Outcome Pathway (AoP) development to support mechanistic risk assessment •Proactively identify and communicate on target and off target safety risks •Collaborate closely with Toxicology, Discovery, Clinical Safety, Bioinformatics, Data Science, and IT teams •Serve as a bridge and clearly communicate complex computational insights to multidisciplinary stakeholders. Qualifications: •Ph.D. in Computational Toxicology, Computational Biology, Bioinformatics, Molecular Biology, or related field •Strong collaboration, scientific leadership, and communication skills, with the ability to translate complex computational results into actionable insights for stakeholders with diverse backgrounds •Expertise in computational toxicology, AI/ML modeling, and multi-omics (TGx) data integration •Familiar with toxicology related data curation, and interpretation, and knowledge of GLP toxicology and regulatory guidance will be a favorable plus •Must be legally authorized to work in the United States without restriction. •Must be willing to take a drug test and post-offer physical (if required) •Must be 18 years of age or older •The base salary range for the Principal position is $140,000 to $222,000. •The base salary range for the Sr. Principal position is $170,0000 to $269,000. Compensation: •$140,000 - $222,000 / year •The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!