Hiring: Senior DMPK Director Company: Exelixis Location: Alameda, CA Job Posted Time: 2026-09-10 11:46:32 About the job Experience: •Minimum 12 years experience in DMPK •Expert knowledge of in vitro and in vivo ADME studies •Strong experience of managing external DMPK work at CROs •Extensive experience in identifying clinical candidates through balancing ADME, pharmacology and toxicology properties and progressing molecules into clinical trials •Solid experience in utilization of physiologically-based and empirical modeling and simulations techniques to characterize drug-drug interactions and biopharmaceutics liabilities Required Skills: •PhD degree in Pharmacokinetics, Drug Metabolism, Pharmaceutical Sciences, or other relevant field and a minimum of 14 years of relevant experience in DMPK in the pharmaceutical industry Qualifications: •Extensive scientific and technical knowledge around drug metabolism and drug transporters, including enzymology and enzyme kinetics and in vitro to in vivo extrapolation •Demonstration of independent thought/creativity in science and drug discovery •In-depth knowledge of current practices and issues in DMPK (including regulatory requirements), PKPD and translational sciences •Keen desire to grow and develop the careers of team members •Demonstrates strong leadership; and has the ability to influence and make decisions •Excellent collaborative verbal and written communication skills •Able to work well with multi-disciplinary teams •Works on problems of diverse scope where analysis and review of data requires evaluation of identifiable factors. Works on ADME complex issues where analysis of situations or data requires an in-depth evaluation of variable factors •Exercises independent judgment in selecting methods, techniques, and evaluation criteria for obtaining results •Networks with key contacts outside own area of expertise Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!