Hiring: (Senior) Director, Translational Medicine and Diagnostics Company: insitro Location: South San Francisco, CA Job Posted Time: 2026-09-12 10:27:05 Employment Type: Hybrid Target Skills & Keywords : GCP About the job Experience: •10+ years of experience in translational science in biotech and/or pharma, including direct experience as a translational lead delivering therapeutics and diagnostic biomarkers from FIH through proof-of-concept to NDA/BLA submission Required Skills: •Translational Strategy & Leadership •Build the Function: Build and lead insitro's translational medicine function, from IND/CTA through clinical proof-of-concept, across biologics, oligonucleotides, and small molecules •Lead Key Assets: Serve as translational lead for advanced pre-clinical and initial clinical-stage assets •Own End-to-End Strategy: Be accountable for translational medicine strategy, GCP adherence, and regulatory-authority interactions, including biospecimen CRO selection and oversight •Design Stratification Strategies: Design innovative approaches to patient stratification using laboratory and digital biomarkers •Generate Proof-of-Mechanism Evidence: Generate proof-of-mechanism evidence that drives objective, data-driven, and timely go/no-go decisions •Interpret Regulatory Requirements: Interpret regulatory translational medicine requirements and quantify the return on investment of translational strategies •Partner Across Functions: Collaborate closely with preclinical, clinical, regulatory, and computational teams Qualifications: •Advanced Degree: Advanced degree in life sciences, technology, chemistry, or a related discipline, or equivalent practical experience •Proven Tenure: 10+ years of experience in translational science in biotech and/or pharma, including direct experience as a translational lead delivering therapeutics and diagnostic biomarkers from FIH through proof-of-concept to NDA/BLA submission •AI/ML Exposure: Experience applying AI/ML approaches to drug discovery and development •Technical Breadth: Deep understanding of diagnostic and device regulations, good clinical practice, clinical trial design and execution, clinical pharmacology, biostatistics, and the application of computation to drug development •Cross-Functional Collaborator: Track record of communicating and collaborating effectively with diverse stakeholders across clinical, translational, computational, and life sciences functions •Motivating Leader: Strong interpersonal skills that inspire others to do their best work •Patient-Driven: Genuine passion for bringing better medicines to patients in need •Our target starting salary for successful US-based applicants for this role is $224,000 - $299,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data. •This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies. •In Addition, Insitro Also Provides Our Employees Compensation: •$224,000 - $299,000 / year Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!