Hiring: Senior Director, Project & Portfolio Management Company: insitro Location: South San Francisco, CA Job Posted Time: 2026-09-10 10:27:05 Employment Type: Hybrid Target Skills & Keywords : LLM, Machine Learning, Portfolio Management, R About the job Experience: •15 years of experience in biotech/pharmaceutical industry in the R&D and clinical development space, including 8+ years in project/portfolio leadership leading cross-functional matrix teams Required Skills: •This role will be hybrid, coming onsite to our South San Francisco headquarters with three days per week in the office. Qualifications: •BS degree required in a life science field, MS or PhD preferred •Minimum of 15 years of experience in biotech/pharmaceutical industry in the R&D and clinical development space, including 8+ years in project/portfolio leadership leading cross-functional matrix teams •Extensive knowledge of the drug development process and deliverables at each stage of the pipeline across at least one preferred drug modality (recombinant biologic, small molecule, oligonucleotide), with deep experience in translational stages, CMC workflows, early commercial assessment and clinical development (IND into Phase 2) •Highly skilled at conventional project management – driving execution while balancing speed, quality, and cost including proficiency with project management tools and software, e.g., critical path analyses, scenario planning, budget and resource management •Exposure to the design and implementation of agentic workflows in a pharma or biotech environment •Solid understanding of metabolism, neuroscience or ophthalmology disease areas and its competitive environment with the ability to take part in strategic discussions •Previous experience in high visibility roles requiring the ability to think strategically and summarize complex information into important concepts for broader communication including executive leaders •Deep experience leading matrix team meetings to enable collaboration, decision-making, and alignment with internal and external customers while leading all aspects of project scope, deliverables, risks, and resources •Demonstrated capacity to resolve complex problems using strong interpersonal skills while building and maintaining positive working relationships with collaborators •Comfortable working in dynamic startup settings; adept at navigating ambiguity, evolving priorities, and time/resource constraints. Compensation: •$264,000 - $298,000 / year Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!