Hiring: Senior Director, LNP Formulation & Process Development Company: Flagship Pioneering Location: Cambridge, MA Job Posted Time: 2026-09-15 17:58:09 Employment Type: Full-time Target Skills & Keywords: LNP formulation, process development, small-scale production, nucleic acid payloads, mRNA, siRNA, gene-editing components, machine learning-guided LNP optimization, targeted particle design, technology transfer, process optimization, non-GMP production, analytical development, translational biology, cross-functional collaboration, client-facing, team leadership Experience: - Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Chemistry, Biochemistry, or related field with 12+ years of relevant industry experience; M.S. with 14+ years; or B.S. with 16+ years - Extensive hands-on experience in LNP formulation and process development - Deep understanding of LNP composition, formation, purification, characterization, and related processes - Proven leadership experience managing and developing scientific teams - Experience serving as a senior technical interface with clients and partners - Experience with non-GMP production for in vitro, in vivo, and preclinical studies Required Skills: - LNP formulation and process development expertise - Technical strategy and best practices development for LNP formulation, process development, characterization, and production - Senior technical leadership across multiple programs, including development strategy, experimental planning, data review, risk mitigation, and technical recommendations - Client and partner interface management, including proposals, project scopes, presentations, and business development support - Oversight of non-GMP production of LNP formulations - Technical troubleshooting, process optimization, technology transfer, and continuous improvement for mRNA, siRNA, gene-editing components, and other nucleic acid payloads - Workflow, documentation, and operational practice establishment to improve quality, reproducibility, efficiency, and scalability - Team leadership, mentoring, and development with resource and capacity management - Cross-functional collaboration with Analytical Development, Translational Biology, Project Management, and other functions Qualifications: - Ph.D., M.S., or B.S. in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Chemistry, Biochemistry, or related field - 12+ years (Ph.D.), 14+ years (M.S.), or 16+ years (B.S.) of relevant industry experience - Extensive hands-on LNP formulation and process development experience - Deep understanding of LNP composition, formation, purification, and characterization - Strong organizational leadership, program execution, and client-facing skills - Collaborative, relentless problem solver with passion for genetic medicines Compensation: Not specified Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don’t miss this opportunity to join a forward-thinking team!