Senior Director, GTM Strategy & Portfolio Planning

BridgeBio - San Francisco, CA

Hiring: Senior Director, GTM Strategy & Portfolio Planning Company: BridgeBio Location: San Francisco, CA Job Posted Time: 2026-09-16 11:47:39 Employment Type: Full-time / Hybrid Target Skills & Keywords : R About the job Experience: •12+ years of commercial biotech or pharmaceutical experience, including 7+ years in marketing, GTM, or portfolio strategy roles Required Skills: •Own the end-to-end GTM strategy for encaleret — market entry sequencing, positioning, and long-range commercial roadmap — from pre-NDA approval through Year 1+ and beyond •Lead marketing portfolio planning across BridgeBio’s endocrine pipeline, building the framework used to prioritize investment, sequence launches, and allocate commercial capacity across current and future assets •Serve as the senior commercial strategist on the encaleret Product Team, embedding market, competitive, and portfolio insight into cross-functional planning with Medical Affairs, Regulatory, Market Access, R&D, and Patient Advocacy •Partner with Value & Access and Finance to align long-term payer strategy, forecasting, and lifecycle planning with the broader endocrine portfolio roadmap •Partner closely with the HCP Marketing, Patient Marketing, and KOL Engagement functions to ensure GTM and portfolio strategy translate into coordinated field execution, serving as the strategic through-line across these teams without direct management authority over them •Build and govern the competitive intelligence, market research, and forecasting infrastructure that informs both encaleret’s launch strategy and portfolio-level decision-making •Develop and present long-term GTM and portfolio strategy updates to senior leadership and the Board of Directors •This is a hybrid, San Francisco Bay Area–based role, with in-office collaboration expected Tuesday through Thursday weekly across our San Francisco and Palo Alto offices, and ~25% travel for key congresses, advisory boards, and field engagement. Qualifications: •Bachelor’s degree required; MBA or advanced science degree preferred •Rare disease launch and GTM strategy experience required; endocrinology or nephrology experience is a significant differentiator •Demonstrated experience building portfolio planning frameworks, resource allocation models, or franchise-level prioritization across multiple assets •Proven ability to lead through influence rather than authority, aligning marketing, medical, access, and R&D stakeholders around a shared strategy in a pre-launch, high-ambiguity environment •Demonstrated capacity to travel ~25% for key congresses, advisory boards, and field engagement •You have demonstrated curiosity and adaptability in adopting AI-powered tools and technologies Compensation: •$265,000 - $290,000 / year •Flexible work environment (work from home / hybrid options) •Competitive benefits and rewards package Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!