Scientist / Sr. Scientist In Vivo Translational Sciences
Altos Labs - San Francisco, CA
Hiring: Scientist / Sr. Scientist In Vivo Translational Sciences Company: Altos Labs Location: San Francisco, CA Job Posted Time: 2026-09-12 11:57:48 Employment Type: Contract About the job Experience: •3-5 years (Scientist) and 6+ years (Sr. Scientist) of industry experience in a drug discovery and development setting •5 years (Scientist) and 6+ years (Sr. Scientist) of industry experience in a drug discovery and development setting Required Skills: •Lead the full lifecycle of in vivo pharmacology studies across multiple projects — providing in vivo pharmacology and physiology expertise from study design and model selection through dosing and in-life monitoring, tissue collection and processing, data analysis, interpretation, and reporting of results to program teams •Contribute to selection of pharmacodynamic and target-engagement readouts •Contribute to building translational strategy by leveraging in vivo research for target validation and candidate progression •Develop, characterize, and implement new animal models; including models of fibrosis and other age-related pathologies •Evaluate and implement new technologies, platforms, and best practices for in vivo research to enhance study efficiency and quality •Execute studies in both mice and rats, including conducting survival surgeries to establish rodent models using aseptic technique •Occasionally execute downstream ex vivo analyses •Maintain detailed documentation of all studies in the electronic lab notebook to ensure data integrity and traceability Qualifications: •Ph.D. in biological sciences with a minimum of 3-5 years (Scientist) and 6+ years (Sr. Scientist) of industry experience in a drug discovery and development setting •Extensive expertise with all aspects of in vivo rodent research in both mice and rats •Strong commitment to animal welfare and a 3Rs-centered approach to experimental design •Excellent communication skills for effective collaboration with internal teams and external CRO partners •Exceptional organizational skills, strong attention to detail, and the ability to work independently and collaboratively in a dynamic environment •Demonstrate creative thinking and a proactive, solution-oriented mindset; able to design, troubleshoot, and refine complex in vivo studies with resourcefulness and innovation •High-level problem-solving ability with strong analytical thinking and the capacity to make practical, data-driven decisions •Applied hands-on capability in molecular and cell biology techniques (RNA/DNA extraction, PCR, Western blot, ELISA, and small molecule/biologic assays) •Willingness and ability to work in a lab/vivarium environment for the majority of working hours, including supporting weekend study needs •The salary range for Redwood City, CA Compensation: •$148,400 - $190,300 / year Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!