Hiring: Scientist I, In Vitro Pharmacology Company: Flagship Pioneering Location: Boston, MA Job Posted Time: 2026-09-13 17:58:09 Employment Type: Full-time Target Skills & Keywords: In Vitro Pharmacology, Cell Biology, Assay Development, Mammalian Cell Culture, Biochemical Assays, Cell-Based Assays, TR-FRET, Lumit, ELISA, Western Blot, Flow Cytometry, Reporter Gene Assays, High Content Imaging, Primary Cell Culture, Drug Discovery Experience: - PhD in molecular or cell biology or related discipline with up to 2 years relevant experience - Industry experience preferred - Experience with primary cell culture and characterization, including tissue dissociation - Experience in assay development and testing in model systems and human systems - Demonstrated ability to independently design, develop, and optimize diverse cell-based functional assays Required Skills: - Technical expertise with mammalian cell culture including establishing and maintaining cell lines, transient and stable transfection, lentiviral transduction, and reporter cell lines - Proficiency in industry-standard cell-based assays and bioanalytical techniques including TR-FRET, Lumit, ELISA, Western blot, flow cytometry, enzymatic activity, and reporter gene assays - Cellular/high content imaging and image analysis (e.g., Incucyte, Phenix) is a plus - Strong understanding of analytical and pre-analytical methods and solutions - Ability to design and execute cell-based and biochemical assays to assess activity, target engagement, and mechanism of action - Conceptualize and develop novel assays for diverse target classes and disease areas - Collaborate cross-functionally with design-make-test teams - Contribute to in vivo and ex vivo pharmacology activities - Ensure rapid generation and accurate reporting of high-quality data - Effective communication of scientific findings to diverse teams Qualifications: - PhD in molecular or cell biology or related discipline - Up to 2 years of relevant experience; industry experience preferred - Highly motivated, broadly skilled cell biologist and assay developer - Passion for driving therapeutic modality innovation in biotechnology - Strong collaborative mindset and ability to work cross-functionally - Excellent communication skills, both informal and at project team meetings Compensation: Not specified Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don’t miss this opportunity to join a forward-thinking team!