Hiring: Scientist I, Discovery Chemistry Company: Arrowhead Pharmaceuticals Location: San Diego, CA Job Posted Time: 2026-09-15 14:41:45 Employment Type: On-site About the job Experience: •8+ years of relevant industry laboratory experience or demonstrated scientific leadership within peptide chemistry. Required Skills: •Design, execute, optimize, and troubleshoot solid-phase peptide synthesis (SPPS) workflows using both automated and manual synthesis techniques. •Purify and characterize peptides using chromatographic and mass spectrometry techniques, including HPLC and LC-MS. •Analyze experimental data, interpret results, and propose next steps to support discovery programs. •Contribute to the design and optimization of novel peptide constructs that support RNAi therapeutic development. •Maintain accurate and well-organized experimental records using electronic laboratory notebooks (ELNs). •Present scientific findings and participate in project team discussions. •Maintain laboratory equipment and ensure compliance with laboratory safety procedures and company policies. •Stay current with emerging technologies and scientific literature in peptide chemistry and drug discovery. Qualifications: •Bachelor's or Master's degree in Chemistry, Biochemistry, or a related scientific discipline. •Strong background in organic chemistry and analytical chemistry. •Applied hands-on capability in solid-phase peptide synthesis (SPPS). •Proficiency in analytical characterization using HPLC, UPLC, and LC-MS. •Excellent experimental design, troubleshooting, and problem-solving skills. •Strong written and verbal communication skills with the ability to effectively present scientific results. •Operational familiarity with biophysical assays used to characterize biomolecular interactions. •Demonstrated ability to work independently while contributing effectively to cross-functional research teams. •California pay range {{:}} $105,000 USD - $115,000 USD •Arrowhead provides competitive salaries and an excellent benefit package. Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!