Hiring: Research Associate II, Structural & Cellular Biology (Proteomics & CryoET) Company: Biohub Location: Redwood City, CA Job Posted Time: 2026-09-10 10:23:45 Target Skills & Keywords : Apex, Python, R About the job Experience: •2 years of experience in an RA I position, or 4 years of relevant, post-graduate research experience. Required Skills: •Maintain, seed, and harvest human iPSC and mammalian cell lines for downstream proteomics and imaging workflows. •Engineer and validate cell lines for proteomics assays (CRISPR endogenous tagging, lentiviral overexpression) . •Prepare samples for proximity labeling (e.g., TurboID) and immunoprecipitation plus crosslinking mass spec. •Prepare cell samples for cryoET and correlative light and electron microscopy (CLEM) experiments including transfections and fluorescence labeling. •Prepare vitrified samples using cryogenic freezing methods such as plunge freezing and high pressure freezing. •Perform cryo FIB milling on vitrified cellular samples using FIB-SEM instruments. •Assist with cryoET data collection, tomogram reconstruction, and visualization. •Interface directly with team members to improve the throughput, reliability, and scalability of proteomics and imaging assays. Qualifications: •Bachelor's or Master's degree in Cell Biology, Biochemistry, Bioengineering, Molecular Biology, or a related discipline (or equivalent experience). •Strong organizational skills and meticulous attention to detail across complex, multi-step experimental workflows. •A dynamic, adaptable, and self-motivated approach, with strong communication skills and the ability to work effectively in a collaborative team. •Enthusiasm for learning new techniques and contributing to cutting-edge, cross-disciplinary research. •Applied hands-on capability in proximity labeling approaches (TurboID, BioID, APEX). •Applied hands-on capability in CRISPR-based genome editing, including sgRNA and donor design. •Exposure to cryo-electron tomography and protein structure prediction. Compensation: •$83,000 - $103,000 / year •This position may be eligible to participate in our discretionary annual performance bonus program Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!