Principal Scientist, Upstream Process Science

ImmunityBio, Inc. - Louisville, CO

Hiring: Principal Scientist, Upstream Process Science Company: ImmunityBio, Inc. Location: Louisville, CO Job Posted Time: 2026-09-03 10:23:45 Employment Type: On-site Target Skills & Keywords : AI About the job Experience: •Previous supervisory experience strongly preferred Required Skills: •Lead and advise internal and external teams in development of efficient and robust microbial and cell culture production for whole cell products, viral vector, recombinant monoclonal antibodies, Fc-fusion, and other proteins for research, clinical, and commercial manufacturing. •Provide high-level technical knowledge in the development of batch, fed batch, and perfusion processes for inoculum expansion and biologics production operations. •Manage the day-to-day activities of the team to include the hiring and training of new team members, coaching employees and monitoring performance •Provide project coordination and high-level technical expertise in process development, process improvement, scale-up, and tech transfer activities. •Guide and advise other technical staff in risk assessment, Design of Experiments (DOE), process characterization, process validation, and process monitoring activities. •Provide input for development programs, and collaborate with discovery, formulation, analytical, quality, regulatory and manufacturing teams. •Draft, review and approve technical protocols, reports, and manufacturing deviation investigations. •Present activities and results interdepartmentally, and to senior management. Qualifications: •Fundamental knowledge of cell and molecular biology, immunology, and/or virology •Possess a high level of honesty and integrity, highly motivated and detail oriented. •Expertise in developing upstream biopharmaceutical production processes. •In-depth knowledge of statistical design of experiments (DOE) used in process development. •Master-level technical knowledge of microbial, cell culture, and harvest operations affecting product quality. •Solid functional working knowledge of quality systems related to process development, clinical and commercial manufacturing. •Demonstrated capacity to advise and collaborate with colleagues within and across departments and corporate entities. •Operational familiarity with downstream purification operations. •Adapts to rapidly changing work environment and shift in priorities. •Possess strong written and verbal communication skills. Compensation: •Flexible work environment (work from home / hybrid options) •This position is eligible for a discretionary bonus and equity award Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!