Hiring: Exec Director, Viral Vector Process Development Company: Gilead Sciences Location: Santa Monica, CA Job Posted Time: 2026-09-09 17:58:10 Employment Type: Full-time Target Skills & Keywords: Viral Vector Process Development, Lentiviral Vector (LVV) Design, CAR T-cell Therapy, Upstream Production, Downstream Purification, Process Scale-up, Technology Transfer, CMC, cGMP, In Vivo Viral Vector, Construct Architecture, Promoter Selection, Transgene Optimization, Cost of Goods, Manufacturing Readiness, Cross-functional Leadership Experience: - Executive-level experience leading end-to-end viral vector development, from construct design through clinical and commercial manufacturing support - Proven track record of technical strategy across clinical and commercial scale, including complex tech transfers and external manufacturing partnerships - Experience leading and building high-performing organizations supporting ex vivo and emerging in vivo applications - Demonstrated ability to influence at executive level while maintaining deep technical expertise - Experience in a matrixed environment, balancing competing priorities across functions Required Skills: - Deep expertise in lentiviral vector (LVV) design, including construct architecture, promoter selection, and transgene optimization - Viral vector process development across upstream production systems (transient and stable) and downstream purification and recovery operations - Process scale-up and technology transfer to clinical and commercial manufacturing sites (internal and external) - LVV life cycle management and manufacturing support capabilities - Driving improvements in viral vector productivity, robustness, and cost of goods - Advancing next-generation capabilities including in vivo viral vector development, platform innovations, and emerging delivery technologies - Strong working knowledge of cGMP regulations and compliance systems, including inspection readiness and audit support - Strategic leadership on cross-functional Product Teams - Collaboration with Research, T cell process development, and Analytical development functions Qualifications: - Accountable for end-to-end viral vector development and technical strategy across clinical and commercial scale - Serves as key partner across Research, Product Teams, Technical Operations, and Analytical functions - Balances deep technical expertise with executive-level influence - Ensures robust, scalable vector platforms while building a high-performing organization - Optimizes viral vector development decisions across the full cell therapy value chain, from transduction efficiency and cell performance to manufacturing robustness and CMC sustainability - Translates early concepts into developable and scalable vector designs in partnership with Research - Aligns vector performance with cellular outcomes alongside T cell process development - Ensures appropriate characterization and control strategies with Analytical development - Contributes to integrated product development, aligning vector design and process decisions with clinical and commercial objectives - Reports to SVP, Global Head of Process Development - On-site presence required (Santa Monica, CA or Oceanside, CA) Compensation: Not specified Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don’t miss this opportunity to join a forward-thinking team!