Hiring: Director/Senior Director Cell Line Development Company: BioSpace Location: Indianapolis, IN Job Posted Time: 2026-09-13 11:44:25 Employment Type: Full-time About the job Experience: •6+ years of biopharmaceutical industry experience, with a sustained record of platform leadership and technical mentoring. Required Skills: •Lead the technical strategy for Lilly CHO cell line development platform by advancing the technical capabilities and workflows that enable the large-molecule portfolio. •Evaluate and deploy emerging molecular, automation, and analytical technologies that increase cell line productivity, enhance target product quality, and shorten CLD timelines. •Champion AI/ML across the CLG workflow to accelerate clone selection and enhance data-driven decision-making. •Serve as the cell line development lead on cross-functional CMC teams, translating platform advances into faster, more robust delivery across the large molecule pipeline. •Mentor and develop scientists and research associates, to establish best practices and data standards that scale the group's capability. •Author and review the technical reports and regulatory documentation (IND, BLA) that carry cell line development through submission. •Build and lead external collaborations through academic partnerships and industry consortia to scout and evaluate emerging cell line development technologies. •Present scientific findings internally and externally through conferences and peer-reviewed publications, strengthening Lilly’s reputation in cell line engineering. Qualifications: •Ph.D. in Biochemistry, Biotechnology, or a related field with 6+ years of biopharmaceutical industry experience, with a sustained record of platform leadership and technical mentoring. •Hands-on expertise in mammalian cell culture, transfection, clone screening, stability assessment, and cell banking. •Proficiency in CRISPR/Cas9-based genome-editing campaigns and application of molecular analytical tools, such as digital PCR and NGS, to assess gene expression dynamics. •Solid functional working knowledge of CMC regulatory expectations for cell line development and submission-ready documentation (IND, BLA). •Demonstrated ability to coach, and mentor scientists, and set technical direction for a team. •Demonstrated capacity to work cross-functionally, plan effectively, and prioritize goals to meet accelerated timelines. •Application of AI/ML in cell line or process development to create predictive models for clone productivity, product quality and/or workflow optimization. •Applied hands-on capability in protein and product-quality characterization methods, including analytical SEC (aSEC), CE-SDS, and capillary isoelectric focusing (cIEF). •Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. •Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is Compensation: •$153,000 - $264,000 / year •Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance) Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!