Director, Analytical Chemistry

BioSpace - Cambridge, MA

Hiring: Director, Analytical Chemistry Company: BioSpace Location: Cambridge, MA Job Posted Time: 2026-09-03 14:41:45 Employment Type: Full-time / Remote Target Skills & Keywords : AI, AutoCAD, CAD, Machine Learning About the job Experience: •9+ years of relevant industry experience; a strong M.S. candidate with significant leadership experience may also be considered. Required Skills: •This role will be in Cambridge, MA. •Lead and develop a high-performing team of analytical scientists and, depending on organizational design, matrix-lead additional scientists across analytical chemistry, characterization, and platform functions supporting discovery-stage mRNA-LNP research. •Set the analytical chemistry vision and strategy for discovery-stage mRNA-LNP programs, ensuring fit-for-purpose analytical capabilities are available to support lipid design, payload evaluation, formulation screening, and candidate advancement. •Serve as the senior analytical partner to medicinal chemistry teams by enabling structure confirmation, purity and impurity profiling, route support, reference standard strategy, and rapid troubleshooting for novel lipids and related small molecules. •Partner closely with computational chemistry and data science teams to translate molecular design hypotheses into analytical learning plans, generate data sets that improve structure-property understanding, and inform iterative design of ionizable lipids and related delivery materials. •Partner cross-functionally with formulation and delivery sciences teams to establish robust analytical workflows for screening and characterizing LNP systems, including support for lipid composition assessment, encapsulation-related analytics, degradation pathways, and physicochemical attribute characterization. •Guide fit-for-purpose analytical method development, optimization, qualification, transfer, and lifecycle management across chromatography, mass spectrometry, spectroscopy, and orthogonal characterization platforms. •Provide scientific leadership in small molecule and lipid structure elucidation, impurity identification, forced degradation or stress studies where relevant, and root-cause analysis of analytical or material quality issues. Compensation: •$167,000 - $300,700 / year •Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Interested candidates, please apply directly through the job posting on company's career page or try via AI auto apply on this platform. Don't miss this opportunity to join a forward-thinking team!